The meaning is legit from a song called Kawoula Biov by Daavi Neba and Patapaa who are Ghanaians. The phrase “sco pa tu manaa” was said by Patapaa in the song which is literally Ghanaian gibberish. It was given a meaning by twitter users “what’s on your mind” or what’s your opinion on a topic.
On twitter when an image is posted with the caption “Sco pa tu manaa” they’re asking for your opinion on the image or what’s on your mind when you see the image.